An Unbiased View of modafinil dosage
An Unbiased View of modafinil dosage
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carbamazepine will lower the extent or impact of modafinil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.
modafinil will enhance the amount or outcome of pantoprazole by influencing hepatic enzyme CYP2C19 metabolism. Slight/Significance Mysterious. Web effect on pantoprazole actions not known because of opposing results of CYP450 enzymes; keep track of
Modafinil Tablets, USP 100mg–White to off white capsule shaped uncoated tablets debossed with AC 132 on just one aspect and plain on other facet. Modafinil Tablets, USP 200 mg – White to off white spherical shaped uncoated tablet scored within the one side with AC over and 133 under and basic on other side.
The quantity of medication that you simply just take is determined by the energy of your drugs. Also, the number of doses you take daily, the time allowed in between doses, as well as the period of time you take the drugs depend on the healthcare trouble for which you happen to be utilizing the medication.
Belzutifan is a CYP2C19 substrate. Coadministration with CYP2C19 inhibitors may improve incidence or severity of adverse results. Watch for anemia and hypoxia and minimize belzutifan dose as proposed.
For treatment of shift work disorder, modafinil 200 mg once daily is taken about one hour ahead of the start of the operate change.
Even so, an increased threat of abortion and intrauterine expansion restriction is noticed in some animal experiments. The dangers and advantages of therapy during pregnancy really should be carefully deemed.[19]
In conditions in which continuous favourable airway tension (CPAP) could be the cure of option for abnormal sleepiness, a maximal effort and hard work to deal with with CPAP for an suitable length of time should be produced just before initiating this drug.
apalutamide will decrease the extent or impact of modafinil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Steer clear of or Use Alternate Drug. Coadministration of apalutamide, a strong CYP3A4 inducer, with drugs that are CYP3A4 substrates can result in decreased exposure to these remedies.
Keep track of Carefully (1)levoketoconazole will enhance the degree or effect of modafinil by influencing hepatic/intestinal enzyme CYP3A4 metabolism.
Stiripentol is often a CYP3A4 inhibitor and inducer. Monitor CYP3A4 substrates coadministered with stiripentol for elevated or lowered consequences. CYP3A4 substrates may possibly require dosage adjustment.
No specific antidote exists for that toxic consequences of the PROVIGIL overdose. This kind of overdoses really should be managed with largely supportive treatment, like cardiovascular monitoring.
Though no specific checking is suggested for patients on modafinil, nurses, pharmacists, and doctors ought to be familiar with the feasible drug-drug interactions, which includes oral contraceptive products. Which is why the prescriber should seek advice from that has a pharmacist and carry out an intensive analysis of all current remedies. Nursing need to keep an eye on affected check here person results in addition to look for signs of adverse reactions at Each individual check out. This interprofessional method will enhance therapy with modafinil. [Amount 5]
In 2008, Cephalon paid out $425m and pleaded responsible to a federal criminal cost concerning its promotion of off-label makes use of for Provigil and two other prescription drugs. ^